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Part I

Provider
Prometric
Format
Computer-based examination; items are presented grouped by domain with one timer for all six domains, an optional break halfway through, and forward-only navigation. The NBCE grades across all six domains and reports one Part I score; individual domains are not scored.
Exam questions
255 items
Passing score
375
Examination outline
  • General Anatomy (20%)
    • Topographical Anatomy - 11% of the General Anatomy domain
    • Topographical Anatomy: Planes of the body and anatomical terminology
    • Topographical Anatomy: Head and neck
    • Topographical Anatomy: Back and thorax
    • Topographical Anatomy: Abdomen, pelvis and perineum
    • Topographical Anatomy: Upper and lower limbs
    • Topographical Anatomy: Integument (including histology)
    • Osteology of the Appendicular Skeleton - 13% of the General Anatomy domain
    • Osteology of the Appendicular Skeleton: Upper limb and shoulder girdle
    • Osteology of the Appendicular Skeleton: Lower limb and pelvis
    • Osteology of the Appendicular Skeleton: Development
    • Osteology of the Appendicular Skeleton: Histology
    • Arthrology and Syndesmology of the Appendicular Skeleton - 11% of the General Anatomy domain
    • Arthrology and Syndesmology of the Appendicular Skeleton: Classification of joints
    • Arthrology and Syndesmology of the Appendicular Skeleton: Articulations of the appendicular skeleton
    • Arthrology and Syndesmology of the Appendicular Skeleton: Biomechanics
    • Myology of the Appendicular Skeleton - 12% of the General Anatomy domain
    • Myology of the Appendicular Skeleton: Upper limb and shoulder (including innervation)
    • Myology of the Appendicular Skeleton: Lower limb and pelvic girdle (including innervation)
    • Myology of the Appendicular Skeleton: Development
    • Myology of the Appendicular Skeleton: Structure and histology
    • Cardiovascular and Lymphatic Systems - 11% of the General Anatomy domain
    • Cardiovascular and Lymphatic Systems: Heart
    • Cardiovascular and Lymphatic Systems: Arteries
    • Cardiovascular and Lymphatic Systems: Veins
    • Cardiovascular and Lymphatic Systems: Lymphatic vessels and lymphoid tissue (including spleen and thymus)
    • Cardiovascular and Lymphatic Systems: Development
    • Cardiovascular and Lymphatic Systems: Histology
    • Digestive System - 11% of the General Anatomy domain
    • Digestive System: Oral cavity and pharynx
    • Digestive System: Digestive viscera
    • Digestive System: Development
    • Digestive System: Histology
    • Respiratory System - 11% of the General Anatomy domain
    • Respiratory System: Nose and sinuses
    • Respiratory System: Larynx, trachea and bronchi
    • Respiratory System: Lungs, pleura and mediastinum
    • Respiratory System: Development
    • Respiratory System: Histology
    • Urogenital System - 10% of the General Anatomy domain
    • Urogenital System: Urinary organs
    • Urogenital System: Male reproductive organs
    • Urogenital System: Female reproductive organs
    • Urogenital System: Development
    • Urogenital System: Histology
    • Endocrine System - 10% of the General Anatomy domain
    • Endocrine System: Endocrine glands and tissues
    • Endocrine System: Development
    • Endocrine System: Histology
  • Spinal Anatomy (22%)
    • Osteology of the Axial Skeleton - 18% of the Spinal Anatomy domain
    • Osteology of the Axial Skeleton: Skull
    • Osteology of the Axial Skeleton: Vertebral column
    • Osteology of the Axial Skeleton: Ribs and sternum
    • Osteology of the Axial Skeleton: Development
    • Myology of the Axial Skeleton - 17% of the Spinal Anatomy domain
    • Myology of the Axial Skeleton: Face and head
    • Myology of the Axial Skeleton: Back and neck
    • Myology of the Axial Skeleton: Thorax and abdomen
    • Myology of the Axial Skeleton: Pelvis and perineum
    • Myology of the Axial Skeleton: Development
    • Arthrology and Syndesmology of the Axial Skeleton - 14% of the Spinal Anatomy domain
    • Arthrology and Syndesmology of the Axial Skeleton: Classification of joints
    • Arthrology and Syndesmology of the Axial Skeleton: Articulations of the axial skeleton
    • Arthrology and Syndesmology of the Axial Skeleton: Biomechanics
    • Anatomy of the Central Nervous System and Related Structures - 18% of the Spinal Anatomy domain
    • Anatomy of the Central Nervous System and Related Structures: Cerebrum
    • Anatomy of the Central Nervous System and Related Structures: Brainstem and cerebellum
    • Anatomy of the Central Nervous System and Related Structures: Spinal cord and meninges
    • Anatomy of the Central Nervous System and Related Structures: Vascular supply and relationships
    • Anatomy of the Central Nervous System and Related Structures: Ventricles and cerebrospinal fluid
    • Anatomy of the Central Nervous System and Related Structures: Development
    • Anatomy of the Central Nervous System and Related Structures: Histology
    • Anatomy of the Peripheral and Autonomic Nervous System - 19% of the Spinal Anatomy domain
    • Anatomy of the Peripheral and Autonomic Nervous System: Spinal nerves, plexuses, and branches
    • Anatomy of the Peripheral and Autonomic Nervous System: Cranial nerves
    • Anatomy of the Peripheral and Autonomic Nervous System: Visceral innervation
    • Anatomy of the Peripheral and Autonomic Nervous System: Cutaneous innervation
    • Anatomy of the Peripheral and Autonomic Nervous System: Development
    • Anatomy of the Peripheral and Autonomic Nervous System: Histology
    • Organs of Special Senses - 14% of the Spinal Anatomy domain
    • Organs of Special Senses: Vision
    • Organs of Special Senses: Audition and equilibrium
    • Organs of Special Senses: Olfaction
    • Organs of Special Senses: Gustation
    • Organs of Special Senses: Development
    • Organs of Special Senses: Histology
  • Physiology (18%)
    • Neurophysiology - 12% of the Physiology domain
    • Neurophysiology: Membrane potentials, action potentials, and synaptic transmission
    • Neurophysiology: Motor function
    • Neurophysiology: Sensory function
    • Neurophysiology: Autonomic function
    • Neurophysiology: Higher cortical function
    • Neurophysiology: Special senses
    • Muscle Physiology - 12% of the Physiology domain
    • Muscle Physiology: Cardiac muscle
    • Muscle Physiology: Skeletal muscle
    • Muscle Physiology: Smooth muscle
    • Cardiovascular Physiology - 12% of the Physiology domain
    • Cardiovascular Physiology: Cardiac pump
    • Cardiovascular Physiology: Electrophysiology of the heart
    • Cardiovascular Physiology: Hemodynamics
    • Cardiovascular Physiology: Regulation of circulation
    • Cardiovascular Physiology: Circulation in organs
    • Cardiovascular Physiology: Lymphatics
    • Cardiovascular Physiology: Hematology and immunity
    • Respiratory Physiology - 11% of the Physiology domain
    • Respiratory Physiology: Mechanics of breathing
    • Respiratory Physiology: Ventilation, lung volumes and capacities
    • Respiratory Physiology: Regulation of respiration
    • Respiratory Physiology: O2 and CO2 transport
    • Respiratory Physiology: Gas exchange
    • Body Fluids and Renal Physiology - 11% of the Physiology domain
    • Body Fluids and Renal Physiology: Regulation of body fluids/micturition
    • Body Fluids and Renal Physiology: Glomerular filtration
    • Body Fluids and Renal Physiology: Tubular exchange
    • Body Fluids and Renal Physiology: Acid-base balance
    • Gastrointestinal Physiology - 10% of the Physiology domain
    • Gastrointestinal Physiology: Ingestion/motility
    • Gastrointestinal Physiology: Digestion/secretion
    • Gastrointestinal Physiology: Absorption
    • Gastrointestinal Physiology: Regulation of GI function
    • Reproductive Physiology - 10% of the Physiology domain
    • Endocrine Physiology - 12% of the Physiology domain
    • Endocrine Physiology: Secretion of hormones
    • Endocrine Physiology: Action of hormones
    • Endocrine Physiology: Regulation
    • Exercise and Sports Physiology - 10% of the Physiology domain
  • Chemistry (13%)
    • Carbohydrates - 13% of the Chemistry domain
    • Carbohydrates: Metabolism
    • Carbohydrates: Metabolism: Catabolic pathways
    • Carbohydrates: Metabolism: Anabolic pathways
    • Carbohydrates: Chemistry
    • Carbohydrates: Chemistry: Structure
    • Carbohydrates: Chemistry: Properties
    • Carbohydrates: Chemistry: Function
    • Carbohydrates: Nutritional concepts
    • Carbohydrates: Nutritional concepts: Food sources
    • Carbohydrates: Nutritional concepts: Digestion
    • Lipids - 12% of the Chemistry domain
    • Lipids: Metabolism
    • Lipids: Metabolism: Catabolic pathways
    • Lipids: Metabolism: Anabolic pathways
    • Lipids: Chemistry
    • Lipids: Chemistry: Structure
    • Lipids: Chemistry: Properties
    • Lipids: Chemistry: Function
    • Lipids: Chemistry: Transport
    • Lipids: Nutritional concepts
    • Lipids: Nutritional concepts: Food sources
    • Lipids: Nutritional concepts: Digestion
    • Proteins, Amino Acids and Peptides - 13% of the Chemistry domain
    • Proteins, Amino Acids and Peptides: Amino acid metabolism
    • Proteins, Amino Acids and Peptides: Amino acid metabolism: Catabolic pathways
    • Proteins, Amino Acids and Peptides: Amino acid metabolism: Anabolic pathways
    • Proteins, Amino Acids and Peptides: Chemistry
    • Proteins, Amino Acids and Peptides: Chemistry: Structure
    • Proteins, Amino Acids and Peptides: Chemistry: Properties
    • Proteins, Amino Acids and Peptides: Chemistry: Function
    • Proteins, Amino Acids and Peptides: Nutritional concepts
    • Proteins, Amino Acids and Peptides: Nutritional concepts: Food sources
    • Proteins, Amino Acids and Peptides: Nutritional concepts: Digestion
    • Enzymes - 12% of the Chemistry domain
    • Enzymes: Classification and function
    • Enzymes: Kinetics and regulation
    • Hormones - 13% of the Chemistry domain
    • Hormones: Metabolic effects of specific hormones
    • Hormones: Metabolic effects of specific hormones: Carbohydrate metabolism
    • Hormones: Metabolic effects of specific hormones: Lipid metabolism
    • Hormones: Metabolic effects of specific hormones: Protein metabolism
    • Hormones: General properties
    • Hormones: General properties: Chemistry
    • Hormones: General properties: Mechanism of action
    • Nucleotides and Nucleic Acids - 12% of the Chemistry domain
    • Nucleotides and Nucleic Acids: Metabolism of purines and pyrimidines
    • Nucleotides and Nucleic Acids: Chemistry
    • Nucleotides and Nucleic Acids: Chemistry: Structure
    • Nucleotides and Nucleic Acids: Chemistry: Properties
    • Nucleotides and Nucleic Acids: Chemistry: Function
    • Nucleotides and Nucleic Acids: DNA, RNA and protein synthesis
    • Vitamins and Minerals - 13% of the Chemistry domain
    • Vitamins and Minerals: Chemistry
    • Vitamins and Minerals: Chemistry: Structure
    • Vitamins and Minerals: Chemistry: Properties
    • Vitamins and Minerals: Chemistry: Function
    • Vitamins and Minerals: Chemistry: Coenzyme precursors
    • Vitamins and Minerals: Nutritional concepts
    • Vitamins and Minerals: Nutritional concepts: Food sources
    • Vitamins and Minerals: Nutritional concepts: Absorption and metabolism
    • Vitamins and Minerals: Nutritional concepts: Storage
    • Biochemical Energetics - 12% of the Chemistry domain
    • Biochemical Energetics: Basic Concepts
    • Biochemical Energetics: Basic Concepts: High-energy phosphate compounds
    • Biochemical Energetics: Basic Concepts: Oxidation-reduction reactions
    • Biochemical Energetics: Citric acid cycle
    • Biochemical Energetics: Oxidative phosphorylation and electron transport system
  • Pathology (16%)
    • Fundamentals of Pathology - 15% of the Pathology domain
    • Fundamentals of Pathology: Disease at the cellular level
    • Fundamentals of Pathology: Inflammation and repair
    • Fundamentals of Pathology: Neoplasia
    • Fundamentals of Pathology: Hemodynamic disorders
    • Genetic and Congenital Disorders - 10% of the Pathology domain
    • Genetic and Congenital Disorders: Chromosomal disorders
    • Genetic and Congenital Disorders: Inborn errors of metabolism
    • Genetic and Congenital Disorders: Congenital disorders
    • Disorders of the Immune System - 14% of the Pathology domain
    • Disorders of the Immune System: Hypersensitivity reactions
    • Disorders of the Immune System: Autoimmune diseases
    • Disorders of the Immune System: Immunologic deficiencies
    • Environmental and Nutritional Diseases - 13% of the Pathology domain
    • Disorders of the Musculoskeletal System - 16% of the Pathology domain
    • Disorders of the Musculoskeletal System: Bone
    • Disorders of the Musculoskeletal System: Joint
    • Disorders of the Musculoskeletal System: Muscle
    • Disorders of the Nervous System - 16% of the Pathology domain
    • Disorders of the Nervous System: Central nervous system
    • Disorders of the Nervous System: Peripheral nervous system
    • Diseases of the Organ Systems - 16% of the Pathology domain
    • Diseases of the Organ Systems: Cardiovascular
    • Diseases of the Organ Systems: Gastrointestinal
    • Diseases of the Organ Systems: Respiratory
    • Diseases of the Organ Systems: Genitourinary
    • Diseases of the Organ Systems: Endocrine
    • Diseases of the Organ Systems: Blood and lymphatics
  • Microbiology (11%)
    • Immunology - 18% of the Microbiology domain
    • Immunology: Cells of the immune system
    • Immunology: Antigens, antibodies and complement
    • Immunology: Hypersensitivities and immunopathologies
    • Immunology: Immunization/vaccination
    • Immunology: Assessment of immune responses/serology
    • Bacteria - 18% of the Microbiology domain
    • Bacteria: Structure and biochemical characteristics
    • Bacteria: Resistance, genetics, antigenicity, and pathogenicity
    • Bacteria: Communicable and infectious diseases
    • Bacteria: Reservoirs of infection and modes of transmission
    • Viruses and Prions - 18% of the Microbiology domain
    • Viruses and Prions: Structure and biochemical characteristics
    • Viruses and Prions: Resistance, genetics, antigenicity, and pathogenicity
    • Viruses and Prions: Communicable and infectious diseases
    • Viruses and Prions: Reservoirs of infection and modes of transmission
    • Fungi - 15% of the Microbiology domain
    • Fungi: Structure and biochemical characteristics
    • Fungi: Resistance, genetics, antigenicity, and pathogenicity
    • Fungi: Communicable and infectious diseases
    • Fungi: Reservoirs of infection and modes of transmission
    • Parasites - 15% of the Microbiology domain
    • Parasites: Structure and biochemical characteristics
    • Parasites: Resistance, genetics, antigenicity, and pathogenicity
    • Parasites: Communicable and infectious diseases
    • Parasites: Reservoirs of infection and modes of transmission
    • Epidemiology and Disease Control - 16% of the Microbiology domain
    • Epidemiology and Disease Control: Health agencies and reporting/monitoring
    • Epidemiology and Disease Control: Prevention, identification and control methods for communicable diseases
    • Epidemiology and Disease Control: Population health assessments
    • Epidemiology and Disease Control: Emerging diseases
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